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2017


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Publication (2017)

Rapid LC-MS Determination of Acromelic Acids A and B, Toxic Constituents of the Mushroom Paralepistopsis acromelalga

Naoki Yoshioka, Hitoshi Ouchi, Toshiyuki Kan, Masashi Yoshida, Motoyuki Nomura
Food Hygiene and Safety Science 58, 241-245 (2017). DOI: 10.3358/shokueishi.58.241

Total Synthesis of TAN1251C via Diastereoselective Construction of the Azaspiro Skeleton

Yosuke Nagasaka, Sayaka Shintaku, Kosuke Matsumura, Akitaka Masuda, Tomohiro Asakawa, Makoto Inai, Masahiro Egi, Yoshitaka Hamashima, Yoshinobu Ishikawa, Toshiyuki Kan
Org. Lett. 19, 3839-3842 (2017). DOI: 10.1021/acs.orglett.7b01718


Efficient Synthesis of 3-Amino-1,5-benzodiazepine-2-one Derivatives

Nobuhiro Obara, Takeshi Watanabe, Tomohiro Asakawa, Toshiyuki Kan, Takao Tanaka
Synlett , 28, 1183-1186 (2017). DOI: 10.1055/s-0036-1588954


Synthetic Study on Pactamycin: Stereoselective Synthesis of the Cyclopentane Core Framework

Goto, Atsumi; Yoshimura, Satoshi; Nakao, Yuta; Inai, Makoto; Asakawa, Tomohiro; Egi, Masahiro; Hamashima, Yoshitaka; Kondo, Mitsuru; Kan, Toshiyuki
Org. Lett. 19, 3358-3361 (2017). DOI: 10.1021/acs.orglett.7b01257


Divergent synthesis of kinase inhibitor derivatives, leading to discovery of selective Gck inhibitors

Takanori Matsumaru, Makoto Inai, Kana Ishigami, Toshiki Iwamatsu, Hiroshi Maita, Satoko Otsuguro, Takao Nomura, Akira Matsuda, Satoshi Ichikawa, Masahiro Sakaitani, Satoshi Shuto, Katsumi Maenaka, Toshiyuki Kan
Bioorg. Med. Chem. Lett. 27, 2144-2147 (2017). DOI: 10.1016/j.bmcl.2017.03.055


Insulinotropic and anti-apoptotic effects of nobiletin in INS-1D ß-cells

Miki Takii, Yukiko K. Kaneko, Kiriko Akiyama, Yuki Aoyagi, Yuki Tara, Tomohiro Asakawa
Makoto Inai, Toshiyuki Kan, Kiyomitsu Nemoto, Tomohisa Ishikawa
J. Funct. Foods , 30, 8–15 (2017). DOI: 10.1016/j.jff.2016.12.037