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2016


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Publications (2016)

Synthesis of chemical-biology tools enabling in vivo imaging and analysis of epigallocatechin gallate

T. Asakawa, A. Yoshida, Y. Hirooka, T. Suzuki, K. Itoh, K. Shimizu, N. Oku, T. Furuta, T. Wakimoto, M. Inai, T. Kan
Heterocycles, 93, 218–242 (2016). DOI: 10.3987/COM-15-S(T)25


Stereoselective Construction of 2-Vinyl 3-Hydroxybenzopyran Rings: Total Syntheses of Teadenols A and B

Yoshida, R.; Ouchi, H.; Yoshida, A.; Asakawa, T.; Inai, M.; Egi, M.; Hamashima, Y.; Kan, T.
Org. Biomol. Chem., 14, 10783–10786 (2016). DOI: 10.1039/C6OB02004F


Concise Synthesis of Anserine: Efficient Solvent Tuning in Asymmetric Hydrogenation Reaction

Megumi Yamashita, Keita Shimizu, Yasuaki Koizumi, Toshiyuki Wakimoto, Yoshitaka Hamashima, Tomohiro Asakawa, Makoto Inai, Toshiyuki Kan*
Synlett, 27, 2734–2736 (2016). DOI: 10.1055/s-0035-1562796


Practical synthesis of spermine, thermospermine and norspermine

Kariya, Y.; Asanuma, Y.; Inai, M.; Asakawa, T.; Ohashi-Ito, K.; Fukuda, H.; Egi, M.; Kan, T.
Chem. Pharm. Bull., 64, 1403–1407 (2016). DOI: 10.1248/cpb.c16-00355


Syntheses of methylated catechins and theaflavins using 2-nitrobenzenesulfonyl group to protect and deactivate phenol

Tomohiro Asakawa, Yusuke Kawabe, Atsushi Yoshida, Yoshiyuki Aihara, Tamiko Manabe, Yoshitsugu Hirose, Asuka Sakurada, Makoto Inai, Yoshitaka Hamashima, Takumi Furuta, Toshiyuki Wakimoto, Toshiyuki Kan*
J. Antibiot., 69, 299-312 (2016). DOI: 10.1038/ja.2016.14

Applications of C-H Insertion Reaction in Total Synthesis of Biologically Active Heterocyclic Natural Products

T. Kan,* T. Asakawa, M. Inai.
Heterocycles, 92, 31-43 (2016) DOI: 10.3987/REV-15-829

Synthesis of food effective constituents toward the development for chemical biology investigations

M. Inai, T. Asakawa, T. Kan.
J. Synth. Org. Chem., Jpn., 74, 412-425 (2016).DOI: 10.5059/yukigoseikyokaishi.74.412


Practical Total Syntheses of Acromelic Acids A and B

Makoto Inai, Hitoshi Ouchi, Aya Asahina, Tomohiro Asakawa, Yoshitaka Hamashima, Toshiyuki Kan
Chem. Pharm. Bull., 64, 723-732 (2016).DOI: 10.1248/cpb.c16-00009


Nobiletin: a citrus flavonoid displaying potent physiological activity

Shuji Noguchi, Haruka Atsumi, Yasunori Iwao, Toshiyuki Kan, Shigeru Itai
Acta Cryst., C72, 124-127 (2016).DOI: 10.1107/S2053229616000577

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