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2013


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Chemical synthesis of tea polyphenols and related compounds

Tomohiro Asakawa, Yoshitaka Hamashima, Toshiyuki Kan
Current Pharmaceutical Design., 19, 6207 (2013). PMID: 23448439

Effects of green tea catechins on cytochrome P450 2B6, 2C8, 2C19, 2D6 and 3A activities in human liver and intestinal microsomes

Misaka, Shingen; Kawabe, Keisuke; Onoue, Satomi; Werba, Jose Pablo; Giroli, Monica; Tamaki, Sekihiro; Kan, Toshiyuki; Kimura, Junko; Watanabe, Hiroshi; Yamada, Shizuo
Drug Metabolism and Pharmacokinetics., 28, 244-249 (2013). DOI: 10.2133/dmpk.DMPK-12-RG-101

Stereocontrolled total synthesis of sphingofungin E

Kazutada Ikeuchi, Moemi Hayashi, Tomohiro Yamamoto, Makoto Inai, Tomohiro Asakawa, Yoshitaka Hamashima, Toshiyuki Kan
Eur. J. Org. Chem., 6789 (2013). DOI: 10.1002/ejoc.201301065

Physicochemical and biopharmaceutical characterization of amorphous solid dispersion of nobiletin, a citrus polymethoxylated flavone, with improved hepatoprotective effects

Satomi Onoue, Tatsuya Nakamura, Atsushi Uchida, Kazunori Ogawa, Kayo Yuminoki, Naofumi Hashimoto, Aiki Hiza, Yuta Tsukaguchi, Tomohiro Asakawa, Toshiyuki Kan, Shizuo Yamada
Euro. J. Pharm. Sci.,49, 453-460 (2013). DOI: 10.1016/j.ejps.2013.05.014

Chemoselective Hydrogenation Reaction of Unsaturated Bonds in the Presence of o-Nitrobenzenesulfonyl Group

Akinori Kawanishi, Chiyako Miyamoto, Yuki Yabe, Makoto Inai, Tomohiro Asakawa, Yoshitaka Hamashima, Hironao Sajiki, Toshiyuki Kan
Org. Lett.,15, 1306-1309 (2013). DOI: 10.1021/ol4002448

Synthesis of Theaflavins via Biomimetic Oxidative Coupling Reactions

Yusuke Kawabe, Yoshiyuki Aihara, Yoshitsugu Hirose, Asuka Sakurada, Atsushi Yoshida, Makoto Inai, Tomohiro Asakawa, Yoshitaka Hamashima, Toshiyuki Kan
Synlett, 24, 479-482 (2013) DOI: 55/s-0032-1318131