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論文発表


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Publications (2022)

Total Synthesis of Isosilybin B
This paper is dedicated to the memory of Professor Toshiyuki Kan, who passed away on July 24th, 2021.
Makoto Inai,* Yoshinori Ueno, Hiroto Sagara, Hitoshi Ouchi, Fumihiko Yoshimura and Toshiyuki Kan,*
Eur. J. Org. Chem. 2022, in press. (DOI: 10.1002/ejoc.202200653)


Controlled Tetradeuteration of Straight-Chain Fatty Acids: Synthesis, Application, and Insight into the Metabolism of Oxidized Linoleic Acid
Ayako Watanabe,‡ Kotaro Hama,*‡ Kohei Watanabe, Yuko Fujiwara, Kazuaki Yokoyama,
Shigeo Murata, and Ryo Takita* (‡ co-first authors)
Angew. Chem. Int. Ed. 2022, 61, e202202779. (DOI: 10.1002/anie.202202779)




This paper has been selected to be highlighted on the front cover.

Ayako Watanabe,‡ Kotaro Hama,*‡ Kohei Watanabe, Yuko Fujiwara, Kazuaki Yokoyama, Shigeo Murata, and Ryo Takita* (‡ co-first authors)

Angew. Chem. Int. Ed. 2022, 61, e202202779. (DOI:10.1002/anie.202207054)
Synthesis of 3-Allylindoles via Annulation of N-Allyl-2-ethynylaniline Derivatives Using a P,Olefin Type Ligand/Pd(0) Catalyst
Takashi Mino,* Toshiki Yamaoka, Kohei Watanabe,* Chihiro Masuda, Shohei Kasano, Yasushi Yoshida, Ryo Takita, Yoshio Kasashima, and Masami Sakamoto
J. Org. Chem. 2022, 87, 7365-7377. (DOI: 10.1021/acs.joc.2c00588)


Mechanistic Details of Asymmetric Bromocyclization with BINAP Monoxide: Identification of Chiral Proton-Bridged Bisphosphine Oxide Complex and Its Application to Parallel Kinetic Resolution
Kenji Yamashita, Ryo Hirokawa, Mamoru Ichikawa, Tatsunari Hisanaga, Yoshihiro Nagao, Ryo Takita,
Kohei Watanabe, Yuji Kawato, and Yoshitaka Hamashima
J. Am. Chem. Soc. 2022, 144, 3913-3924. (DOI: 10.1021/jacs.1c11816)


Generation of organo-alkaline earth metal complexes from non-polar unsaturated molecules and their synthetic applications
Kohei Watanabe‡, Jia Hao Pang‡, Ryo Takita,* and Shunsuke Chiba* (‡ co-first authors)
Chem. Sci. 2022, 13, 27-38. (perspective) (DOI: 10.1039/D1SC05724C)

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1,2,3-Triazine formation mechanism of the fairy chemical 2-azahypoxanthine in the fairy ring-forming fungus Lepista sordida
Akinobu Ito,‡ Jae-Hoon Choi,‡ Waki Yokoyama-Maruyama, Mihaya Kotajima, Jing Wu, Tomohiro Suzuki,
Yurika Terashima, Hyogo Suzuki, Hirofumi Hirai, David C. Nelson, Yuta Tsunematsu, Kenji Watanabe,
Tomohiro Asakawa, Hitoshi Ouchi, Makoto Inai, Hideo Dohra, Hirokazu Kawagishi*
(‡ These authors contributed equally to this work.)
Org. Biomol. Chem. 2022, 2636–2642. (DOI: 10.1039/D2OB00328G)